Diet analysis suggests lipid imbalance slows cancer  Giulia Salvadori & Valter D. Longo

Understanding how diet affects tumour growth could lead to better treatments. Analysis in mice reveals that a low-calorie diet, but not a ketogenic diet, slows the growth of pancreatic cancer. This effect is mediated by lipid changes.

BMC CANCER / 2018
The effects of short-term fasting on quality of life and tolerance to chemotherapy in patients with breast and ovarian cancer: a randomized cross-over pilot study

JOP. JOURNAL OF THE PANCREAS / 2018
Long-Term Outcomes of the Treatment of Unresectable (StageIII- IV) Ductal Pancreatic Adenocarcinoma Using Metabolically Supported Chemotherapy (MSCT): A Retrospective Study

CELL PRESS / 2018
Starvation, Stress Resistance, and Cancer

SCIENTIFIC REPORTS / 2017
Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice

PLOS|BIOLOGY / 2017

Fasting regulates EGR1 and protects from glucose- and dexamethasone-dependent sensitization to chemotherapy

ELSEVIER / 2017
Protective effects of short-term dietary restriction in surgical stress and chemotherapy

SCIENTIFIC REPORTS / 2017
Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice

AACR / 2016
Targeting Cancer Metabolism: Dietary and Pharmacologic Interventions

BIOMED CENTRAL / 2016
Safety and feasibility of fasting in combination with platinum based chemotherapy

CELL PRESS / 2016
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity

ELSEVIER / 2016
Growth factors, aging and age-related diseases

BMC CANCER / 2015
The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study

IMPACT JOURNALS / 2015
Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition

IMPACT JOURNALS / 2015
Fasting induces anti-warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models

DISCOVER / 2013
A small group of Ecuadorians with rare genetic disorder could hold a key to cancer and other age-related illness.

NATIONAL INSTITUTE OF HEALTH / 2013
Aging, Nutrient Signaling, Hematopoietic Senescence, and Cancer

SCIENCE TRANSLATIONAL MEDICINE / 2012
Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

ELSEVIER / 2012
Starvation, detoxification, and multi drug resistance in cancer therapy

C Lee and VD Longo / 2011
Fasting vs dietary restriction in cellular protection and cancer treatment:from model organisms to patients

JOVE / 2011
Video ArticleStudying Age-dependent Genomic Instability using theS. cerevisiae Chronological Lifespan Model

CANCER RESEARCH / 2010
Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fastingand Improve Chemotherapeutic Index

JCB / 2009
Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Pol-dependent mechanism

IMPACT AGING / 2009
Fasting and cancer treatment in humans: A case series report

PNAS / 2008
Starvation-dependent differential stress resistanceprotects normal but not cancer cells againsthigh-dose chemotherapy

PERSPECTIVES / 2008
Turning anti aging genes against cancer

JCB / 2008
Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system

ELSEVIER / 2007
A simple model system for age-dependent DNA damage and cancer