Rare genetic condition may offer protection from heart disease

A new study has revealed that a rare genetic condition, known as growth hormone receptor deficiency (GHRD) or Laron syndrome, may protect against cardiovascular disease.

The body’s ineffective use of its own growth hormone characterizes this condition, leading to stunted growth. Researchers have long observed in mice that this mutation significantly increases lifespan and reduces age-related diseases; however, only recently have they begun to understand its impact on human cardiovascular health.

What is Laron Syndrome?

Laron Syndrome is a rare genetic condition that primarily affects growth due to a defect in the growth hormone receptor. This defect disrupts the normal action of growth hormone, a critical regulator of growth, metabolism, and body composition.

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